HIV-1 Gag specifically restricts PI(4,5)P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assembly
HIV-1 Gag protein assembles at the plasma membrane of infected cells for viral particle formation. Gag targets lipids, mainly PI(4,5)P2, at the inner leaflet of this membrane. Here, we address the question whether Gag is able to trap specifically PI(4,5)P2 or other lipids during HIV-1 assembly in th...
Những tác giả chính: | Favard, C, Chojnacki, J, Merida, P, Yandrapalli, N, Mak, J, Eggeling, C, Muriaux, D |
---|---|
Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
American Association for the Advancement of Science
2019
|
Những quyển sách tương tự
-
Specific Lipid Recruitment by the Retroviral Gag Protein upon HIV-1 Assembly: From Model Membranes to Infected Cells
Bằng: Cyril Favard, et al.
Được phát hành: (2020-06-01) -
Lipid domains in HIV-1 assembly
Bằng: Naresh eYandrapalli, et al.
Được phát hành: (2014-05-01) -
Role of Gag and lipids during HIV-1 assembly in CD4 T cells and Macrophages
Bằng: Charlotte eMariani, et al.
Được phát hành: (2014-06-01) -
Targeting of MuLV Gag to the plasma membrane is mediated by PI(4,5)P<sub>2 </sub>and PhosphatidylSerine
Bằng: Summers Michael F, et al.
Được phát hành: (2009-09-01) -
Multivalent chelator lipids for targeting proteins into membrane nanodomains
Bằng: Beutel, O, et al.
Được phát hành: (2011)