T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component.

T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component.

Stimulation of the T cell antigen receptor (TCR) induces formation of a phosphorylation-dependent signaling network via multiprotein complexes, whose compositions and dynamics are incompletely understood. Using stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative proteom...

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Bibliographic Details
Main Authors: Brockmeyer, C, Paster, W, Pepper, D, Tan, C, Trudgian, D, McGowan, S, Fu, G, Gascoigne, N, Acuto, O, Salek, M
Format: Journal article
Language:English
Published: 2011

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