meCLICK-Seq, a substrate-hijacking and RNA degradation strategy for the study of RNA methylation

The fates of RNA species in a cell are controlled by ribonucleases, which degrade them by exploiting the universal structural 2′-OH group. This phenomenon plays a key role in numerous transformative technologies, for example, RNA interference and CRISPR/Cas13-based RNA editing systems. Th...

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Bibliographic Details
Main Authors: Shi, Y, Mikutis, S, Gu, M, Sendinc, E, Hazemi, ME, Kiely-Collins, H, Aspris, D, Vassiliou, GS, Tzelepis, K, Bernardes, GJL
Format: Journal article
Language:English
Published: ACS Publications 2020