Population Pharmacokinetics of Dihydroartemisinin and Piperaquine in Pregnant and Nonpregnant Women with Uncomplicated Malaria

Pregnant women are particularly vulnerable to malaria. The pharmacokinetic properties of antimalarial drugs are often affected by pregnancy, resulting in lower drug concentrations and a consequently higher risk of treatment failure. The objective of this study was to evaluate the population pharmaco...

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Detalhes bibliográficos
Principais autores: Tarning, J, Rijken, M, McGready, R, Phyo, A, Hanpithakpong, W, Day, N, White, N, Nosten, F, Lindegardh, N
Formato: Journal article
Idioma:English
Publicado em: American Society for Microbiology 2012