TRICARBONYLCHROMIUM(0) PROMOTED STEREOSELECTIVE CYCLIZATIONS OF THE N-3,4-DIMETHOXYPHENETHYL DERIVATIVES OF THE 1-PHENYL ETHANOLAMINES HALOSTACHINE, EPHEDRINE AND PSEUDOEPHEDRINE TO 1-PHENYL-N-METHYL-7,8-DIMETHOXY-1,2,4,5-TETRAHYDROBENZAZEPINES
Acid promoted cyclisation of homochiral (R)-N-(3,4-dimethoxyphenethyl)-halostachine proceeds with almost total racemisation to yield 1-phenyl-N-methyl-1,2,4,5-tetrahydrobenz[d]azepine (e.e. 6%). Coordination of the cyclisation precursor to the tricarbonylchromium(0) moiety renders the cyclisation co...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1990
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