Metabolic changes during carcinogenesis: Potential impact on invasiveness

Successful adaptation to varying microenvironmental constraints plays a crucial role during carcinogenesis. We develop a hybrid cellular automation approach to investigate the cell–microenvironmental interactions that mediate somatic evolution of cancer cells. This allows investigation of the hypoth...

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Bibliografische gegevens
Hoofdauteurs: Smallbone, K, Gatenby, R, Gillies, R, Maini, P, Gavaghan, D
Formaat: Journal article
Gepubliceerd in: 2007