Ca2+ and synaptic plasticity
The induction and maintenance of synaptic plasticity is well established to be a Ca2+-dependent process. The use of fluorescent imaging to monitor changes [Ca2+]i in neurones has revealed a diverse array of signaling patterns across the different compartments of the cell. The Ca2+ signals within the...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2005
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| _version_ | 1797076786669944832 |
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| author | Cavazzini, M Bliss, T Emptage, N |
| author_facet | Cavazzini, M Bliss, T Emptage, N |
| author_sort | Cavazzini, M |
| collection | OXFORD |
| description | The induction and maintenance of synaptic plasticity is well established to be a Ca2+-dependent process. The use of fluorescent imaging to monitor changes [Ca2+]i in neurones has revealed a diverse array of signaling patterns across the different compartments of the cell. The Ca2+ signals within these compartments are generated by voltage or ligand-gated Ca2+ influx, and release from intracellular stores. The changes in [Ca2+]i are directly linked to the activity of the neurone, thus a neurone's input and output is translated into a dynamic Ca2+ code. Despite considerable progress in measuring this code much still remains to be determined in order to understand how the code is interpreted by the Ca2+ sensors that underlie the induction of compartment-specific plastic changes. © 2005 Published by Elsevier Ltd. |
| first_indexed | 2024-03-07T00:08:43Z |
| format | Journal article |
| id | oxford-uuid:78784cbd-a04a-4e07-888e-bd18eef8f280 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:08:43Z |
| publishDate | 2005 |
| record_format | dspace |
| spelling | oxford-uuid:78784cbd-a04a-4e07-888e-bd18eef8f2802022-03-26T20:30:49ZCa2+ and synaptic plasticityJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:78784cbd-a04a-4e07-888e-bd18eef8f280EnglishSymplectic Elements at Oxford2005Cavazzini, MBliss, TEmptage, NThe induction and maintenance of synaptic plasticity is well established to be a Ca2+-dependent process. The use of fluorescent imaging to monitor changes [Ca2+]i in neurones has revealed a diverse array of signaling patterns across the different compartments of the cell. The Ca2+ signals within these compartments are generated by voltage or ligand-gated Ca2+ influx, and release from intracellular stores. The changes in [Ca2+]i are directly linked to the activity of the neurone, thus a neurone's input and output is translated into a dynamic Ca2+ code. Despite considerable progress in measuring this code much still remains to be determined in order to understand how the code is interpreted by the Ca2+ sensors that underlie the induction of compartment-specific plastic changes. © 2005 Published by Elsevier Ltd. |
| spellingShingle | Cavazzini, M Bliss, T Emptage, N Ca2+ and synaptic plasticity |
| title | Ca2+ and synaptic plasticity |
| title_full | Ca2+ and synaptic plasticity |
| title_fullStr | Ca2+ and synaptic plasticity |
| title_full_unstemmed | Ca2+ and synaptic plasticity |
| title_short | Ca2+ and synaptic plasticity |
| title_sort | ca2 and synaptic plasticity |
| work_keys_str_mv | AT cavazzinim ca2andsynapticplasticity AT blisst ca2andsynapticplasticity AT emptagen ca2andsynapticplasticity |