Squaramide‐based 5’‐phosphate replacements bind to the DNA repair exonuclease SNM1A
Phosphate groups are often crucial to biological activity and interactions of oligonucleotides, but confer poor membrane permeability. In addition, the group's lability to enzymatic hydrolysis is an obstacle to its use in therapeutics and in biological tools. We present the synthesis of N‐oxyam...
| Main Authors: | , , , , , , , |
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| Format: | Journal article |
| Published: |
Wiley
2018
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