Direct ex vivo analysis reveals distinct phenotypic patterns of HIV-specific CD8(+) T lymphocyte activation in response to therapeutic manipulation of virus load.

Therapeutic intervention with antiretroviral therapy (ART) enables the modulation of HIV virus load and hence provides a unique opportunity to study the consequences of varying antigen load on the phenotype of virus-specific CD8(+) T lymphocytes in a persistent human viral infection. The recent adve...

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Những tác giả chính: Oxenius, A, Günthard, H, Hirschel, B, Fidler, S, Weber, J, Easterbrook, P, Bell, J, Phillips, R, Price, D
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2001