Direct ex vivo analysis reveals distinct phenotypic patterns of HIV-specific CD8(+) T lymphocyte activation in response to therapeutic manipulation of virus load.
Therapeutic intervention with antiretroviral therapy (ART) enables the modulation of HIV virus load and hence provides a unique opportunity to study the consequences of varying antigen load on the phenotype of virus-specific CD8(+) T lymphocytes in a persistent human viral infection. The recent adve...
Principais autores: | Oxenius, A, Günthard, H, Hirschel, B, Fidler, S, Weber, J, Easterbrook, P, Bell, J, Phillips, R, Price, D |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
2001
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