The role of IGF-1R signaling in the DNA damage response of prostate cancer

The role of IGF-1R signaling in the DNA damage response of prostate cancer

<p>The type 1 insulin like growth factor receptor (IGF-1R) is a cell surface receptor that mediates proliferation and cell survival. The aim of this project was to explore the contribution of the IGF-1R to the DNA damage response in human prostate cancer cells. Previous work from our group s...

Descrizione completa

Dettagli Bibliografici
Autore principale:	Lodhia, K
Altri autori:	Macaulay, V
Natura:	Tesi
Lingua:	English
Pubblicazione:	2013
Soggetti:	Medical Sciences Urology Biology Oncology

Documenti analoghi

Investigating the biology of nuclear IGF-1R in prostate cancer
di: Mills, JV
Pubblicazione: (2021)

B2B: Prostate Cancer Summary
di: Stacy Loeb, Peter C. Black, Alexander W. Wyatt, Yaw A. Nyame, Neal Shore, Derya Tilki, Elena Castro, Matthew Cooperberg, Veda Giri, Maria J. Ribal, Giovanni Lughezzani, Rafael Sánchez-Salas, Caroline M. Moore, Art Rastinehad, Linda Kerkmeijer, Hashim U. Ahmed, Shusuke Akamatsu, Alexandre de la Taille, Martin Gleave, Simon Tanguay
Pubblicazione: (2021-07-01)

The evaluation of the IGF-1R as a proposed biomarker for DNA damaging cancer therapies
di: Worrall, R
Pubblicazione: (2014)

The role of hypoxia in urological malignancies
di: Blick, C, et al.
Pubblicazione: (2012)

Distinct microRNA alterations characterize high- and low-grade bladder cancer
di: Catto, J, et al.
Pubblicazione: (2009)

Novel signalling pathways regulating epithelial-mesenchymal transition in bone metastatic prostate cancer
di: Rao, SR
Pubblicazione: (2014)

Using machine learning models to predict synchronous genitourinary cancers among gastrointestinal stromal tumor patients
di: Mohammad Alghafees, et al.
Pubblicazione: (2024-01-01)

B2B: Kidney Cancer Summary
di: Simon Tanguay, E. Jason Abel, Laurence Albigès, Toni Choueiri, Axel Bex, Umberto Capitanio, Maxine Tran, Alessandro Volpe, Peter Black
Pubblicazione: (2021-07-01)

The Assessment of SF-36 Survey for Quality-of-Life Measurement after Radical Cystectomy for Muscle-Invasive Bladder Cancer: A Systematic Review
di: Vlad Barbos, et al.
Pubblicazione: (2024-03-01)

Investigating high circulating IGF-1 as a risk factor for development of prostate cancer
di: Nandakumar, AM
Pubblicazione: (2022)

Distinct effects of sacituzumab govitecan and berzosertib on DNA damage response in ovarian cancer
di: Jayakumar R. Nair, et al.
Pubblicazione: (2024-12-01)

Stereotactic Body Therapy for Urologic Cancers—What the Urologist Needs to Know
di: Jasamine Coles-Black, et al.
Pubblicazione: (2024-12-01)

Clinical and Pathological Characteristics of Bladder Cancer in Patients Aged 18–45 Undergoing Transurethral Resection of Bladder Tumor
di: Alexei Croitor, et al.
Pubblicazione: (2024-10-01)

Personalized Medicine in Urologic Oncology
di: Yair Lotan, Jack Schalken, Nathan Lawrentschuk
Pubblicazione: (2020-10-01)

The impact of uro-oncology multidisciplinary team meeting (MDTM) on clinical decision-making and adherence to MDTM recommendation: experience from a tertiary referral centre in Malaysia
di: Norshuhada Amat, et al.
Pubblicazione: (2024-03-01)

Active surveillance for prostate cancer: to whom, when and how
di: M. S. Taratkin, et al.
Pubblicazione: (2019-09-01)

Targeting EGFR signalling pathway in triple negative breast cancer
di: Albukhari, A
Pubblicazione: (2014)

Targeting EGFR signalling pathway in triple negative breast cancer
di: Albukhari, A
Pubblicazione: (2014)

The role of Wee1 in the hypoxia-induced DNA damage response and its potential as a therapeutic target
di: O'Brien, EM
Pubblicazione: (2012)

Investigating the role of IGF-1R in the cellular response to DNA damage
di: Petnga Kamdoum, WV
Pubblicazione: (2017)

The role of LATS1 in DNA damage signalling
di: Latusek, R
Pubblicazione: (2012)

Uro-Oncology Multidisciplinary Team Meetings at an Australian Tertiary Centre: A Detailed Analysis of Cases, Decision Outcomes, Impacts on Patient Treatment, Documentation, and Clinician Attendance
di: Ramesh Shanmugasundaram, et al.
Pubblicazione: (2024-08-01)

Role and regulation of MITF in melanocytes and melanoma
di: Siddaway, RT
Pubblicazione: (2014)

Investigations on anti-IGF-1R therapy response in a colorectal cancer cell line panel
di: Puschhof, J
Pubblicazione: (2016)

The role of ABCC5 in metabolism and signalling in prostate cancer
di: Abele, J
Pubblicazione: (2024)

The role of DLL4-NOTCH signalling in endothelial cell metabolism
di: Harjes, U
Pubblicazione: (2014)

The role of homeobox gene NKX3.1 in prostate cancer
di: Patel, R
Pubblicazione: (2014)

The Combined Effect of Downregulated RB1 and Overexpressed lncRNA SSTRS-AS1 on Prediction Time to Castration-Resistant Prostate Cancer: Indonesian Cohort Studies
di: Soerohardjo, Indrawarman, et al.
Pubblicazione: (2022)

Does the IGF-1R have a role in the DNA damage response?
di: Macaulay, V
Pubblicazione: (2012)

Investigating the transcriptional response of rDNA to hypoxia
di: Ng, N
Pubblicazione: (2021)

The role of astrocytes in brain metastasis
di: O'Brien, E
Pubblicazione: (2014)

Report on the conference of the Russian association of oncological urology in Volgograd in 2018
di: I. V. Aleksandrov, et al.
Pubblicazione: (2018-10-01)

APPROACHES FOR A MODEL OF POPULATION UROLOGICAL SCREENING BASED ON TELEMEDICINE TECHNOLOGIES
di: O. I. Apolikhin, et al.
Pubblicazione: (2017-10-01)

Renal Cell Carcinoma Migrating to the Right Atrium through the Inferior Vena Cava
di: Mohamad Bakir, et al.
Pubblicazione: (2022-09-01)

Editorial: Rising stars in urologic oncology: 2021
di: Juan Gómez Rivas, et al.
Pubblicazione: (2023-10-01)

Base excision repair of radiation-induced DNA damage in mammalian cells
di: Cooper, S, et al.
Pubblicazione: (2013)

Critical roles of lncRNA-mediated autophagy in urologic malignancies
di: Lifeng Gan, et al.
Pubblicazione: (2024-06-01)

PSA testing for prostate cancer: an online survey of the views and reported practice of General Practitioners in the UK
di: Brett, J, et al.
Pubblicazione: (2005)

A rare case of collecting duct renal cell carcinoma
di: Vance Gentry, et al.
Pubblicazione: (2024-03-01)

The role of ATF4 in hypoxia-induced cell death in cancer
di: Pike, L, et al.
Pubblicazione: (2011)