The role of IGF-1R signaling in the DNA damage response of prostate cancer

The role of IGF-1R signaling in the DNA damage response of prostate cancer

<p>The type 1 insulin like growth factor receptor (IGF-1R) is a cell surface receptor that mediates proliferation and cell survival. The aim of this project was to explore the contribution of the IGF-1R to the DNA damage response in human prostate cancer cells. Previous work from our group s...

Полное описание

Библиографические подробности
Главный автор:	Lodhia, K
Другие авторы:	Macaulay, V
Формат:	Диссертация
Язык:	English
Опубликовано:	2013
Предметы:	Medical Sciences Urology Biology Oncology

Схожие документы

Investigating the biology of nuclear IGF-1R in prostate cancer
по: Mills, JV
Опубликовано: (2021)

B2B: Prostate Cancer Summary
по: Stacy Loeb, Peter C. Black, Alexander W. Wyatt, Yaw A. Nyame, Neal Shore, Derya Tilki, Elena Castro, Matthew Cooperberg, Veda Giri, Maria J. Ribal, Giovanni Lughezzani, Rafael Sánchez-Salas, Caroline M. Moore, Art Rastinehad, Linda Kerkmeijer, Hashim U. Ahmed, Shusuke Akamatsu, Alexandre de la Taille, Martin Gleave, Simon Tanguay
Опубликовано: (2021-07-01)

The evaluation of the IGF-1R as a proposed biomarker for DNA damaging cancer therapies
по: Worrall, R
Опубликовано: (2014)

The role of hypoxia in urological malignancies
по: Blick, C, и др.
Опубликовано: (2012)

Distinct microRNA alterations characterize high- and low-grade bladder cancer
по: Catto, J, и др.
Опубликовано: (2009)

Novel signalling pathways regulating epithelial-mesenchymal transition in bone metastatic prostate cancer
по: Rao, SR
Опубликовано: (2014)

Using machine learning models to predict synchronous genitourinary cancers among gastrointestinal stromal tumor patients
по: Mohammad Alghafees, и др.
Опубликовано: (2024-01-01)

B2B: Kidney Cancer Summary
по: Simon Tanguay, E. Jason Abel, Laurence Albigès, Toni Choueiri, Axel Bex, Umberto Capitanio, Maxine Tran, Alessandro Volpe, Peter Black
Опубликовано: (2021-07-01)

The Assessment of SF-36 Survey for Quality-of-Life Measurement after Radical Cystectomy for Muscle-Invasive Bladder Cancer: A Systematic Review
по: Vlad Barbos, и др.
Опубликовано: (2024-03-01)

Investigating high circulating IGF-1 as a risk factor for development of prostate cancer
по: Nandakumar, AM
Опубликовано: (2022)

Distinct effects of sacituzumab govitecan and berzosertib on DNA damage response in ovarian cancer
по: Jayakumar R. Nair, и др.
Опубликовано: (2024-12-01)

Stereotactic Body Therapy for Urologic Cancers—What the Urologist Needs to Know
по: Jasamine Coles-Black, и др.
Опубликовано: (2024-12-01)

Clinical and Pathological Characteristics of Bladder Cancer in Patients Aged 18–45 Undergoing Transurethral Resection of Bladder Tumor
по: Alexei Croitor, и др.
Опубликовано: (2024-10-01)

Personalized Medicine in Urologic Oncology
по: Yair Lotan, Jack Schalken, Nathan Lawrentschuk
Опубликовано: (2020-10-01)

The impact of uro-oncology multidisciplinary team meeting (MDTM) on clinical decision-making and adherence to MDTM recommendation: experience from a tertiary referral centre in Malaysia
по: Norshuhada Amat, и др.
Опубликовано: (2024-03-01)

Active surveillance for prostate cancer: to whom, when and how
по: M. S. Taratkin, и др.
Опубликовано: (2019-09-01)

Targeting EGFR signalling pathway in triple negative breast cancer
по: Albukhari, A
Опубликовано: (2014)

Targeting EGFR signalling pathway in triple negative breast cancer
по: Albukhari, A
Опубликовано: (2014)

The role of Wee1 in the hypoxia-induced DNA damage response and its potential as a therapeutic target
по: O'Brien, EM
Опубликовано: (2012)

Investigating the role of IGF-1R in the cellular response to DNA damage
по: Petnga Kamdoum, WV
Опубликовано: (2017)

The role of LATS1 in DNA damage signalling
по: Latusek, R
Опубликовано: (2012)

Uro-Oncology Multidisciplinary Team Meetings at an Australian Tertiary Centre: A Detailed Analysis of Cases, Decision Outcomes, Impacts on Patient Treatment, Documentation, and Clinician Attendance
по: Ramesh Shanmugasundaram, и др.
Опубликовано: (2024-08-01)

Role and regulation of MITF in melanocytes and melanoma
по: Siddaway, RT
Опубликовано: (2014)

Investigations on anti-IGF-1R therapy response in a colorectal cancer cell line panel
по: Puschhof, J
Опубликовано: (2016)

The role of ABCC5 in metabolism and signalling in prostate cancer
по: Abele, J
Опубликовано: (2024)

The role of DLL4-NOTCH signalling in endothelial cell metabolism
по: Harjes, U
Опубликовано: (2014)

The role of homeobox gene NKX3.1 in prostate cancer
по: Patel, R
Опубликовано: (2014)

The Combined Effect of Downregulated RB1 and Overexpressed lncRNA SSTRS-AS1 on Prediction Time to Castration-Resistant Prostate Cancer: Indonesian Cohort Studies
по: Soerohardjo, Indrawarman, и др.
Опубликовано: (2022)

Does the IGF-1R have a role in the DNA damage response?
по: Macaulay, V
Опубликовано: (2012)

Investigating the transcriptional response of rDNA to hypoxia
по: Ng, N
Опубликовано: (2021)

The role of astrocytes in brain metastasis
по: O'Brien, E
Опубликовано: (2014)

Report on the conference of the Russian association of oncological urology in Volgograd in 2018
по: I. V. Aleksandrov, и др.
Опубликовано: (2018-10-01)

APPROACHES FOR A MODEL OF POPULATION UROLOGICAL SCREENING BASED ON TELEMEDICINE TECHNOLOGIES
по: O. I. Apolikhin, и др.
Опубликовано: (2017-10-01)

Renal Cell Carcinoma Migrating to the Right Atrium through the Inferior Vena Cava
по: Mohamad Bakir, и др.
Опубликовано: (2022-09-01)

Editorial: Rising stars in urologic oncology: 2021
по: Juan Gómez Rivas, и др.
Опубликовано: (2023-10-01)

Base excision repair of radiation-induced DNA damage in mammalian cells
по: Cooper, S, и др.
Опубликовано: (2013)

Critical roles of lncRNA-mediated autophagy in urologic malignancies
по: Lifeng Gan, и др.
Опубликовано: (2024-06-01)

PSA testing for prostate cancer: an online survey of the views and reported practice of General Practitioners in the UK
по: Brett, J, и др.
Опубликовано: (2005)

A rare case of collecting duct renal cell carcinoma
по: Vance Gentry, и др.
Опубликовано: (2024-03-01)

The role of ATF4 in hypoxia-induced cell death in cancer
по: Pike, L, и др.
Опубликовано: (2011)