The Functional quality of soluble recombinant polypeptides produced in Escherichia coli is defined by a wide conformational spectrum.
We have observed that a soluble recombinant green fluorescent protein produced in Escherichia coli occurs in a wide conformational spectrum. This results in differently fluorescent protein fractions in which morphologically diverse soluble aggregates abound. Therefore, the functional quality of solu...
| 主要な著者: | , , , |
|---|---|
| フォーマット: | Journal article |
| 言語: | English |
| 出版事項: |
2008
|
| 要約: | We have observed that a soluble recombinant green fluorescent protein produced in Escherichia coli occurs in a wide conformational spectrum. This results in differently fluorescent protein fractions in which morphologically diverse soluble aggregates abound. Therefore, the functional quality of soluble versions of aggregation-prone recombinant proteins is defined statistically rather than by the prevalence of a canonical native structure. |
|---|