Splicing of many human genes involves sites embedded within introns.

The conventional model for splicing involves excision of each intron in one piece; we demonstrate this inaccurately describes splicing in many human genes. First, after switching on transcription of SAMD4A, a gene with a 134 kb-long first intron, splicing joins the 3' end of exon 1 to successiv...

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Main Authors: Kelly, S, Georgomanolis, T, Zirkel, A, Diermeier, S, O'Reilly, D, Murphy, S, Längst, G, Cook, P, Papantonis, A
格式: Journal article
语言:English
出版: Oxford University Press 2015