Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development.
Hematopoiesis is initiated in several distinct tissues in the mouse conceptus. The aorta-gonad-mesonephros (AGM) region is of particular interest, as it autonomously generates the first adult type hematopoietic stem cells (HSCs). The ventral position of hematopoietic clusters closely associated with...
Main Authors: | Peeters, M, Ottersbach, K, Bollerot, K, Orelio, C, De Bruijn, M, Wijgerde, M, Dzierzak, E |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2009
|
Similar Items
-
Developmental origins of hematopoietic stem cells.
by: Robin, C, et al.
Published: (2003) -
From hemangioblast to hematopoietic stem cell: an endothelial connection?
by: Jaffredo, T, et al.
Published: (2005) -
Isolation and analysis of hematopoietic stem cells from mouse embryos.
by: Dzierzak, E, et al.
Published: (2002) -
COMMITMENT OF ENDOTHELIAL CELLS TO A HEMATOPOIETIC FATE IN THE AGM OCCURS BEFORE E10.5
by: Swiers, G, et al.
Published: (2010) -
Rat embryonic mast cells originate in the AGM.
by: Michel Farchi Guiraldelli, et al.
Published: (2013-01-01)