Protein interactions in human genetic diseases.

We present a novel method that combines protein structure information with protein interaction data to identify residues that form part of an interaction interface. Our prediction method can retrieve interaction hotspots with an accuracy of 60% (at a 20% false positive rate). The method was applied...

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Bibliographic Details
Main Authors: Schuster-Böckler, B, Bateman, A
Format: Journal article
Language:English
Published: 2008

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