Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand.
Retrospective case series from Thailand have reported the presence of intra-abdominal abscesses in around half of patients with melioidosis, a much higher rate than our clinical experience would suggest. We performed a prospective, observational study of 230 adult patients with culture-confirmed mel...
Main Authors: | , , , , , , , , , |
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Format: | Journal article |
Language: | English |
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2012
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author | Maude, R Vatcharapreechasakul, T Ariyaprasert, P Maude, R Hongsuwan, M Yuentrakul, P Limmathurotsakul, D Koh, G Chaowagul, W Day, N Peacock, S |
author_facet | Maude, R Vatcharapreechasakul, T Ariyaprasert, P Maude, R Hongsuwan, M Yuentrakul, P Limmathurotsakul, D Koh, G Chaowagul, W Day, N Peacock, S |
author_sort | Maude, R |
collection | OXFORD |
description | Retrospective case series from Thailand have reported the presence of intra-abdominal abscesses in around half of patients with melioidosis, a much higher rate than our clinical experience would suggest. We performed a prospective, observational study of 230 adult patients with culture-confirmed melioidosis in which all patients underwent abdominal ultrasound. One or more abscesses were detected in the liver and/or spleen in 77 (33%) cases. These were often multiple (70%, 31/44 in hepatic abscesses and 88%, 50/57 in splenic abscesses) and clinically silent (27% of cases with abscesses presenting with abdominal pain). The mortality rate at 4 weeks post-discharge was lower in patients who were abscess-positive vs abscess-negative (10%, 8/77 vs 20%, 31/153). |
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format | Journal article |
id | oxford-uuid:7907a2d3-04ce-4986-956c-280009d4a759 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T00:10:24Z |
publishDate | 2012 |
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spelling | oxford-uuid:7907a2d3-04ce-4986-956c-280009d4a7592022-03-26T20:34:44ZProspective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7907a2d3-04ce-4986-956c-280009d4a759EnglishSymplectic Elements at Oxford2012Maude, RVatcharapreechasakul, TAriyaprasert, PMaude, RHongsuwan, MYuentrakul, PLimmathurotsakul, DKoh, GChaowagul, WDay, NPeacock, SRetrospective case series from Thailand have reported the presence of intra-abdominal abscesses in around half of patients with melioidosis, a much higher rate than our clinical experience would suggest. We performed a prospective, observational study of 230 adult patients with culture-confirmed melioidosis in which all patients underwent abdominal ultrasound. One or more abscesses were detected in the liver and/or spleen in 77 (33%) cases. These were often multiple (70%, 31/44 in hepatic abscesses and 88%, 50/57 in splenic abscesses) and clinically silent (27% of cases with abscesses presenting with abdominal pain). The mortality rate at 4 weeks post-discharge was lower in patients who were abscess-positive vs abscess-negative (10%, 8/77 vs 20%, 31/153). |
spellingShingle | Maude, R Vatcharapreechasakul, T Ariyaprasert, P Maude, R Hongsuwan, M Yuentrakul, P Limmathurotsakul, D Koh, G Chaowagul, W Day, N Peacock, S Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand. |
title | Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand. |
title_full | Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand. |
title_fullStr | Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand. |
title_full_unstemmed | Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand. |
title_short | Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand. |
title_sort | prospective observational study of the frequency and features of intra abdominal abscesses in patients with melioidosis in northeast thailand |
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