Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand.

Retrospective case series from Thailand have reported the presence of intra-abdominal abscesses in around half of patients with melioidosis, a much higher rate than our clinical experience would suggest. We performed a prospective, observational study of 230 adult patients with culture-confirmed mel...

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Main Authors: Maude, R, Vatcharapreechasakul, T, Ariyaprasert, P, Hongsuwan, M, Yuentrakul, P, Limmathurotsakul, D, Koh, G, Chaowagul, W, Day, N, Peacock, S
Format: Journal article
Language:English
Published: 2012
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author Maude, R
Vatcharapreechasakul, T
Ariyaprasert, P
Maude, R
Hongsuwan, M
Yuentrakul, P
Limmathurotsakul, D
Koh, G
Chaowagul, W
Day, N
Peacock, S
author_facet Maude, R
Vatcharapreechasakul, T
Ariyaprasert, P
Maude, R
Hongsuwan, M
Yuentrakul, P
Limmathurotsakul, D
Koh, G
Chaowagul, W
Day, N
Peacock, S
author_sort Maude, R
collection OXFORD
description Retrospective case series from Thailand have reported the presence of intra-abdominal abscesses in around half of patients with melioidosis, a much higher rate than our clinical experience would suggest. We performed a prospective, observational study of 230 adult patients with culture-confirmed melioidosis in which all patients underwent abdominal ultrasound. One or more abscesses were detected in the liver and/or spleen in 77 (33%) cases. These were often multiple (70%, 31/44 in hepatic abscesses and 88%, 50/57 in splenic abscesses) and clinically silent (27% of cases with abscesses presenting with abdominal pain). The mortality rate at 4 weeks post-discharge was lower in patients who were abscess-positive vs abscess-negative (10%, 8/77 vs 20%, 31/153).
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spelling oxford-uuid:7907a2d3-04ce-4986-956c-280009d4a7592022-03-26T20:34:44ZProspective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7907a2d3-04ce-4986-956c-280009d4a759EnglishSymplectic Elements at Oxford2012Maude, RVatcharapreechasakul, TAriyaprasert, PMaude, RHongsuwan, MYuentrakul, PLimmathurotsakul, DKoh, GChaowagul, WDay, NPeacock, SRetrospective case series from Thailand have reported the presence of intra-abdominal abscesses in around half of patients with melioidosis, a much higher rate than our clinical experience would suggest. We performed a prospective, observational study of 230 adult patients with culture-confirmed melioidosis in which all patients underwent abdominal ultrasound. One or more abscesses were detected in the liver and/or spleen in 77 (33%) cases. These were often multiple (70%, 31/44 in hepatic abscesses and 88%, 50/57 in splenic abscesses) and clinically silent (27% of cases with abscesses presenting with abdominal pain). The mortality rate at 4 weeks post-discharge was lower in patients who were abscess-positive vs abscess-negative (10%, 8/77 vs 20%, 31/153).
spellingShingle Maude, R
Vatcharapreechasakul, T
Ariyaprasert, P
Maude, R
Hongsuwan, M
Yuentrakul, P
Limmathurotsakul, D
Koh, G
Chaowagul, W
Day, N
Peacock, S
Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand.
title Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand.
title_full Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand.
title_fullStr Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand.
title_full_unstemmed Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand.
title_short Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand.
title_sort prospective observational study of the frequency and features of intra abdominal abscesses in patients with melioidosis in northeast thailand
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