B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPL2A.

Eitemau Tebyg

• MUTATIONS IN THE INTRAMEMBRANE ENDOPEPTIDASE SPPL2A AFFECT HUMORAL IMMUNITY AND B-CELL SURVIVAL BY REDUCING SURFACE BCR AND BAFF-R EXPRESSION AND AFFECTING CD74 METABOLISM
  gan: Bergmann, H, et al.
  Cyhoeddwyd: (2012)
• Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival.
  gan: Ferry, H, et al.
  Cyhoeddwyd: (2005)
• Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival (vol 35, pg 3655, 2005)
  gan: Ferry, H, et al.
  Cyhoeddwyd: (2005)
• Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection.
  gan: Cornall, R, et al.
  Cyhoeddwyd: (1998)
• Erratum: Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22- independent pathways affecting BCR regulation and B cell survival (European Journal of Immunology (2005) vol. 35 (12) (3714) 10.1002/eji.200535247)
  gan: Ferry, H, et al.
  Cyhoeddwyd: (2005)