WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complex.

The UAF1 (Usp1-associated factor 1) protein binds and stimulates three deubiquitinating enzymes: USP1, USP12, and USP46. Although the USP1 x UAF1 complex is required for regulation of the Fanconi anemia (FA) DNA repair pathway, less is known about the USP12 x UAF1 and the USP46 x UAF1 complexes. To...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Kee, Y, Yang, K, Cohn, M, Haas, W, Gygi, S, D'Andrea, A
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2010