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MEDI 73-Modeling, synthetic, crystallographic, and activity studies of novel bisphosphonates as inhibitors of farnesyl pyrophosphate synthase

MEDI 73-Modeling, synthetic, crystallographic, and activity studies of novel bisphosphonates as inhibitors of farnesyl pyrophosphate synthase

Dades bibliogràfiques
Autors principals: Hogan, J, Deprele, S, Kashemirov, B, Barnett, B, Evdokimov, A, Dunford, J, Russell, R, Ebetino, F, McKenna, C
Format: Journal article
Publicat: 2007
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  • Evidence for the involvement of the threonine 201 side-chain in the interaction of nitrogen-containing bisphosphonates with farnesyl pyrophosphate synthase
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  • Analysis of the kinetic mechanism of inhibition of Farnesyl Pyrophosphate Synthase by nitrogen containing bisphosphonates.
    per: Dunford, J, et al.
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