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  • MEDI 73-Modeling, synthetic, c...
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MEDI 73-Modeling, synthetic, crystallographic, and activity studies of novel bisphosphonates as inhibitors of farnesyl pyrophosphate synthase

MEDI 73-Modeling, synthetic, crystallographic, and activity studies of novel bisphosphonates as inhibitors of farnesyl pyrophosphate synthase

Bibliográfalaš dieđut
Váldodahkkit: Hogan, J, Deprele, S, Kashemirov, B, Barnett, B, Evdokimov, A, Dunford, J, Russell, R, Ebetino, F, McKenna, C
Materiálatiipa: Journal article
Almmustuhtton: 2007
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  • A mirror image pair of bisphosphonate analogs further demonstrates the mode of binding of the bisphosphonates in farnesyl pyrophosphate synthase
    Dahkki: Ebetino, F, et al.
    Almmustuhtton: (2008)
  • The mode of binding of nitrogen containing bisphosphonates in farnesyl pyrophosphate synthase
    Dahkki: Ebetino, F, et al.
    Almmustuhtton: (2007)
  • The Role of Active Site Threonine 201 in the Inhibition of Farnesyl Pyrophosphate Synthase by Nitrogen Containing Bisphosphonates
    Dahkki: Dunford, J, et al.
    Almmustuhtton: (2008)
  • Evidence for the involvement of the threonine 201 side-chain in the interaction of nitrogen-containing bisphosphonates with farnesyl pyrophosphate synthase
    Dahkki: Kwassi, A, et al.
    Almmustuhtton: (2009)
  • Analysis of the kinetic mechanism of inhibition of Farnesyl Pyrophosphate Synthase by nitrogen containing bisphosphonates.
    Dahkki: Dunford, J, et al.
    Almmustuhtton: (2006)

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