MEDI 73-Modeling, synthetic, crystallographic, and activity studies of novel bisphosphonates as inhibitors of farnesyl pyrophosphate synthase

Liknande verk

• A mirror image pair of bisphosphonate analogs further demonstrates the mode of binding of the bisphosphonates in farnesyl pyrophosphate synthase
  av: Ebetino, F, et al.
  Publicerad: (2008)
• The mode of binding of nitrogen containing bisphosphonates in farnesyl pyrophosphate synthase
  av: Ebetino, F, et al.
  Publicerad: (2007)
• The Role of Active Site Threonine 201 in the Inhibition of Farnesyl Pyrophosphate Synthase by Nitrogen Containing Bisphosphonates
  av: Dunford, J, et al.
  Publicerad: (2008)
• Evidence for the involvement of the threonine 201 side-chain in the interaction of nitrogen-containing bisphosphonates with farnesyl pyrophosphate synthase
  av: Kwassi, A, et al.
  Publicerad: (2009)
• Analysis of the kinetic mechanism of inhibition of Farnesyl Pyrophosphate Synthase by nitrogen containing bisphosphonates.
  av: Dunford, J, et al.
  Publicerad: (2006)