The cost-effectiveness of parasitologic diagnosis for malaria-suspected patients in an era of combination therapy.
The introduction of artemisinin-based combination therapy in sub-Saharan Africa has prompted calls for increased use of parasitologic diagnosis for malaria. We evaluated the cost-effectiveness of rapid diagnostic tests (RDTs) in comparison to microscopy in guiding treatment of non-severe febrile ill...
| 主要な著者: | , , , , , , |
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| フォーマット: | Journal article |
| 言語: | English |
| 出版事項: |
2007
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| _version_ | 1826280246482042880 |
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| author | Lubell, Y Reyburn, H Mbakilwa, H Mwangi, R Chonya, K Whitty, C Mills, A |
| author_facet | Lubell, Y Reyburn, H Mbakilwa, H Mwangi, R Chonya, K Whitty, C Mills, A |
| author_sort | Lubell, Y |
| collection | OXFORD |
| description | The introduction of artemisinin-based combination therapy in sub-Saharan Africa has prompted calls for increased use of parasitologic diagnosis for malaria. We evaluated the cost-effectiveness of rapid diagnostic tests (RDTs) in comparison to microscopy in guiding treatment of non-severe febrile illness at varying levels of malaria endemicity using data on test accuracy and costs collected as part of a Tanzanian trial. If prescribers complied with current guidelines, microscopy would give rise to lower average costs per patient correctly treated than RDTs in areas of both high and low transmission. RDT introduction would result in an additional 2.3% and 9.4% of patients correctly treated, at an incremental cost of $25 and $7 in the low and high transmission settings, respectively. Cost-effectiveness would be worse if prescribers do not comply with test results. The cost of this additional benefit may be higher than many countries can afford without external assistance or lower RDT prices. |
| first_indexed | 2024-03-07T00:10:49Z |
| format | Journal article |
| id | oxford-uuid:792c3920-51eb-49df-85f1-db757e347171 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:10:49Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:792c3920-51eb-49df-85f1-db757e3471712022-03-26T20:35:38ZThe cost-effectiveness of parasitologic diagnosis for malaria-suspected patients in an era of combination therapy.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:792c3920-51eb-49df-85f1-db757e347171EnglishSymplectic Elements at Oxford2007Lubell, YReyburn, HMbakilwa, HMwangi, RChonya, KWhitty, CMills, AThe introduction of artemisinin-based combination therapy in sub-Saharan Africa has prompted calls for increased use of parasitologic diagnosis for malaria. We evaluated the cost-effectiveness of rapid diagnostic tests (RDTs) in comparison to microscopy in guiding treatment of non-severe febrile illness at varying levels of malaria endemicity using data on test accuracy and costs collected as part of a Tanzanian trial. If prescribers complied with current guidelines, microscopy would give rise to lower average costs per patient correctly treated than RDTs in areas of both high and low transmission. RDT introduction would result in an additional 2.3% and 9.4% of patients correctly treated, at an incremental cost of $25 and $7 in the low and high transmission settings, respectively. Cost-effectiveness would be worse if prescribers do not comply with test results. The cost of this additional benefit may be higher than many countries can afford without external assistance or lower RDT prices. |
| spellingShingle | Lubell, Y Reyburn, H Mbakilwa, H Mwangi, R Chonya, K Whitty, C Mills, A The cost-effectiveness of parasitologic diagnosis for malaria-suspected patients in an era of combination therapy. |
| title | The cost-effectiveness of parasitologic diagnosis for malaria-suspected patients in an era of combination therapy. |
| title_full | The cost-effectiveness of parasitologic diagnosis for malaria-suspected patients in an era of combination therapy. |
| title_fullStr | The cost-effectiveness of parasitologic diagnosis for malaria-suspected patients in an era of combination therapy. |
| title_full_unstemmed | The cost-effectiveness of parasitologic diagnosis for malaria-suspected patients in an era of combination therapy. |
| title_short | The cost-effectiveness of parasitologic diagnosis for malaria-suspected patients in an era of combination therapy. |
| title_sort | cost effectiveness of parasitologic diagnosis for malaria suspected patients in an era of combination therapy |
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