Cloxyquin (5-chloroquinolin-8-ol) is an activator of the two-pore domain potassium channel TRESK

Cloxyquin (5-chloroquinolin-8-ol) is an activator of the two-pore domain potassium channel TRESK

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TRESK is a two-pore domain potassium channel. Loss of function mutations have been linked to typical migraine with aura and due to TRESK's expression pattern and role in neuronal excitability it represents a promising therapeutic target. We developed a cell based assay using baculovirus transdu...

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Bibliographic Details
Main Authors:	Wright, P, Weir, G, Cartland, J, Tickle, D, Kettleborough, C, Cader, M, Jerman, J
Format:	Journal article
Language:	English
Published:	2013

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