Which measures of cigarette dependence are predictors of smoking cessation during pregnancy? Analysis of data from a randomized controlled trial

To examine the ability of different common measures of cigarette dependence to predict smoking cessation during pregnancy.Secondary analysis of data from a parallel-group randomized controlled trial of physical activity for smoking cessation. The outcomes were biochemically validated smoking abstine...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Riaz, M, Lewis, S, Coleman, T, Aveyard, P, West, R, Naughton, F, Ussher, M
स्वरूप: Journal article
भाषा:English
प्रकाशित: Wiley 2016
_version_ 1826280257720680448
author Riaz, M
Lewis, S
Coleman, T
Aveyard, P
West, R
Naughton, F
Ussher, M
author_facet Riaz, M
Lewis, S
Coleman, T
Aveyard, P
West, R
Naughton, F
Ussher, M
author_sort Riaz, M
collection OXFORD
description To examine the ability of different common measures of cigarette dependence to predict smoking cessation during pregnancy.Secondary analysis of data from a parallel-group randomized controlled trial of physical activity for smoking cessation. The outcomes were biochemically validated smoking abstinence at 4 weeks post-quit and end-of-pregnancy.Women identified as smokers in antenatal clinics in 13 hospital trusts predominantly in southern England, who were recruited to a smoking cessation trial.Of 789 pregnant smokers recruited, 784 were included in the analysis.Using random-effect logistic regression models, we analysed the effects of baseline measures of cigarette dependence, including numbers of cigarettes smoked daily, Fagerström Test of Cigarette Dependence (FTCD) score, the two FTCD subscales of Heaviness of Smoking Index (HSI) and non-Heaviness of Smoking Index (non-HSI), expired carbon monoxide (CO) level and urges to smoke (strength and frequency) on smoking cessation. Associations were adjusted for significant socio-demographic/health behaviour predictors and trial variables, and area under the receiver operating characteristic (ROC) curve was used to determine the predictive ability of the model for each measure of dependence.All the dependence variables predicted abstinence at 4 weeks and end-of-pregnancy. At 4 weeks, the adjusted odds ratio (OR) (95% confidence interval) for a unit standard deviation increase in FTCD was 0.59 (0.47-0.74), expired CO = 0.54 (0.41-0.71), number of cigarettes smoked per day 0.65 (0.51-0.84) and frequency of urges to smoke 0.79 (0.63-0.98); at end-of-pregnancy they were: 0.60 (0.45-0.81), 0.55 (0.37-0.80), 0.70 (0.49-0.98) and 0.69 (0.51-0.94), respectively. HSI and non-HSI exhibited similar results to the full FTCD.Four common measures of dependence, including number of cigarettes smoked per day, scores for Fagerström Test of Cigarette Dependence and frequency of urges and level of expired CO, all predicted smoking abstinence in the short term during pregnancy and at end-of-pregnancy with very similar predictive validity.
first_indexed 2024-03-07T00:10:59Z
format Journal article
id oxford-uuid:7937aff6-9947-4adb-adbf-2fb8b6b1cdfd
institution University of Oxford
language English
last_indexed 2024-03-07T00:10:59Z
publishDate 2016
publisher Wiley
record_format dspace
spelling oxford-uuid:7937aff6-9947-4adb-adbf-2fb8b6b1cdfd2022-03-26T20:36:00ZWhich measures of cigarette dependence are predictors of smoking cessation during pregnancy? Analysis of data from a randomized controlled trialJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7937aff6-9947-4adb-adbf-2fb8b6b1cdfdEnglishSymplectic Elements at OxfordWiley2016Riaz, MLewis, SColeman, TAveyard, PWest, RNaughton, FUssher, MTo examine the ability of different common measures of cigarette dependence to predict smoking cessation during pregnancy.Secondary analysis of data from a parallel-group randomized controlled trial of physical activity for smoking cessation. The outcomes were biochemically validated smoking abstinence at 4 weeks post-quit and end-of-pregnancy.Women identified as smokers in antenatal clinics in 13 hospital trusts predominantly in southern England, who were recruited to a smoking cessation trial.Of 789 pregnant smokers recruited, 784 were included in the analysis.Using random-effect logistic regression models, we analysed the effects of baseline measures of cigarette dependence, including numbers of cigarettes smoked daily, Fagerström Test of Cigarette Dependence (FTCD) score, the two FTCD subscales of Heaviness of Smoking Index (HSI) and non-Heaviness of Smoking Index (non-HSI), expired carbon monoxide (CO) level and urges to smoke (strength and frequency) on smoking cessation. Associations were adjusted for significant socio-demographic/health behaviour predictors and trial variables, and area under the receiver operating characteristic (ROC) curve was used to determine the predictive ability of the model for each measure of dependence.All the dependence variables predicted abstinence at 4 weeks and end-of-pregnancy. At 4 weeks, the adjusted odds ratio (OR) (95% confidence interval) for a unit standard deviation increase in FTCD was 0.59 (0.47-0.74), expired CO = 0.54 (0.41-0.71), number of cigarettes smoked per day 0.65 (0.51-0.84) and frequency of urges to smoke 0.79 (0.63-0.98); at end-of-pregnancy they were: 0.60 (0.45-0.81), 0.55 (0.37-0.80), 0.70 (0.49-0.98) and 0.69 (0.51-0.94), respectively. HSI and non-HSI exhibited similar results to the full FTCD.Four common measures of dependence, including number of cigarettes smoked per day, scores for Fagerström Test of Cigarette Dependence and frequency of urges and level of expired CO, all predicted smoking abstinence in the short term during pregnancy and at end-of-pregnancy with very similar predictive validity.
spellingShingle Riaz, M
Lewis, S
Coleman, T
Aveyard, P
West, R
Naughton, F
Ussher, M
Which measures of cigarette dependence are predictors of smoking cessation during pregnancy? Analysis of data from a randomized controlled trial
title Which measures of cigarette dependence are predictors of smoking cessation during pregnancy? Analysis of data from a randomized controlled trial
title_full Which measures of cigarette dependence are predictors of smoking cessation during pregnancy? Analysis of data from a randomized controlled trial
title_fullStr Which measures of cigarette dependence are predictors of smoking cessation during pregnancy? Analysis of data from a randomized controlled trial
title_full_unstemmed Which measures of cigarette dependence are predictors of smoking cessation during pregnancy? Analysis of data from a randomized controlled trial
title_short Which measures of cigarette dependence are predictors of smoking cessation during pregnancy? Analysis of data from a randomized controlled trial
title_sort which measures of cigarette dependence are predictors of smoking cessation during pregnancy analysis of data from a randomized controlled trial
work_keys_str_mv AT riazm whichmeasuresofcigarettedependencearepredictorsofsmokingcessationduringpregnancyanalysisofdatafromarandomizedcontrolledtrial
AT lewiss whichmeasuresofcigarettedependencearepredictorsofsmokingcessationduringpregnancyanalysisofdatafromarandomizedcontrolledtrial
AT colemant whichmeasuresofcigarettedependencearepredictorsofsmokingcessationduringpregnancyanalysisofdatafromarandomizedcontrolledtrial
AT aveyardp whichmeasuresofcigarettedependencearepredictorsofsmokingcessationduringpregnancyanalysisofdatafromarandomizedcontrolledtrial
AT westr whichmeasuresofcigarettedependencearepredictorsofsmokingcessationduringpregnancyanalysisofdatafromarandomizedcontrolledtrial
AT naughtonf whichmeasuresofcigarettedependencearepredictorsofsmokingcessationduringpregnancyanalysisofdatafromarandomizedcontrolledtrial
AT ussherm whichmeasuresofcigarettedependencearepredictorsofsmokingcessationduringpregnancyanalysisofdatafromarandomizedcontrolledtrial