Patterns of selective constraint across the mouse and human genomes
<p>Understanding how genetic variation affects organism phenotype and fitness is a fundamental question in biology with implications for biomedical research. Constrained genomic loci (i.e. loci under selective constraint) are depleted of variation due to negative selection and are inferred to...
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| Format: | Thesis |
| Language: | English |
| Published: |
2022
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