Baricitinib versus placebo or adalimumab in rheumatoid arthritis

Baricitinib versus placebo or adalimumab in rheumatoid arthritis

<h4>Background</h4> <p>Baricitinib is an oral, reversible, JAK1/JAK2 inhibitor that may have therapeutic value in patients with rheumatoid arthritis.</p> <h4>Methods</h4> <p>In this 52-week, phase 3, double-blind, placebo and active-controlled study, 1307 p...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Taylor, P, Keystone, E, Van der Heijde, D, Weinblatt, M, del Carmen Morales, L, Reyes Gonzaga, J, Yakushin, S, Ishii, T, Emoto, K, Beattie, S, Arora, V, Gaich, C, Rooney, T, Schlichting, D, Macias, W, de Bono, S, Tanaka, Y
التنسيق:	Journal article
منشور في:	Massachusetts Medical Society 2017

مواد مشابهة

Baricitinib contre placebo ou adalimumab chez des patients atteints de polyarthrite rhumatoïde (PR) active et présentant une réponse inadéquate au méthotrexate (MTX) : Résultats d’une étude de phase 3 de 52 semaines RA-BEAM
حسب: Taylor, P, وآخرون
منشور في: (2016)

Patient-reported outcomes from a phase 3 study of baricitinib versus placebo or adalimumab in rheumatoid arthritis: secondary analyses from the RA-BEAM study
حسب: Keystone, E, وآخرون
منشور في: (2017)

Rapid and sustained pain improvement in rheumatoid arthritis patients treated with baricitinib compared to adalimumab or placebo
حسب: Taylor, P, وآخرون
منشور في: (2017)

Microarray pathway analysis comparing baricitinib and adalimumab in moderate to severe rheumatoid arthritis patients, from a Phase 3 study
حسب: Emery, P, وآخرون
منشور في: (2017)

Efficacy and safety of switching from adalimumab to baricitinib: Phase 3 data in patients with rheumatoid arthritis
حسب: Taylor, P, وآخرون
منشور في: (2016)

Efficacy and safety of switching from adalimumab to baricitinib: phase 3 data in patients with rheumatoid arthritis
حسب: Taylor, P, وآخرون
منشور في: (2017)

Efficacy and safety of switching from adalimumab to baricitinib: long-term data from phase 3 extension study in patients with rheumatoid arthritis
حسب: Weinblatt, M, وآخرون
منشور في: (2018)

Improved patient-reported outcomes in patients with rheumatoid arthritis who failed adalimumab or placebo treatment and were rescued with baricitinib
حسب: Fautrel, B, وآخرون
منشور في: (2017)

Clinical outcomes in patients switched from adalimumab to baricitinib due to non-response and/or study design: phase III data in patients with rheumatoid arthritis
حسب: Tanaka, Y, وآخرون
منشور في: (2019)

Safety and efficacy of baricitinib through 128 weeks in an open-label, longterm extension study in patients with rheumatoid arthritis
حسب: Keystone, EC, وآخرون
منشور في: (2017)

Safety and efficacy of baricitinib at 24 weeks in patients with rheumatoid arthritis who have had an inadequate response to methotrexate.
حسب: Keystone, E, وآخرون
منشور في: (2015)

Temporary interruption of baricitinib: characterization of interruptions and effect on clinical outcomes in patients with rheumatoid arthritis
حسب: Paul Emery, وآخرون
منشور في: (2020-05-01)

Characterization and changes of lymphocyte subsets in baricitinib-treated patients with rheumatoid arthritis: an integrated analysis
حسب: Tanaka, Y, وآخرون
منشور في: (2018)

Cardiovascular safety during treatment with baricitinib in rheumatoid arthritis
حسب: Weinblatt, M, وآخرون
منشور في: (2017)

Correction to: Temporary interruption of baricitinib: characterization of interruptions and effect on clinical outcomes in patients with rheumatoid arthritis
حسب: Paul Emery, وآخرون
منشور في: (2020-07-01)

Effects of baricitinib on lipid, apolipoprotein, and lipoprotein particle profiles in a phase 2b study in patients with active rheumatoid arthritis
حسب: Kremer, J, وآخرون
منشور في: (2017)

Cardiovascular safety during treatment with baricitinib in rheumatoid arthritis
حسب: Taylor, P, وآخرون
منشور في: (2019)

Baricitinib provides greater improvements in patient-reported outcomes across all disease activity levels compared to placebo and adalimumab in rheumatoid arthritis
حسب: Taylor, P, وآخرون
منشور في: (2021)

Effect of baricitinib and adalimumab in reducing pain and improving function in patients with rheumatoid arthritis in low disease activity: exploratory analyses from RA-BEAM
حسب: Fautrel, B, وآخرون
منشور في: (2019)

Efficacy and safety of baricitinib versus placebo and adalimumab in patients with moderately to severely active rheumatoid arthritis and inadequate response to methotrexate: Summary results from the 52-week phase 3 RA-beam study
حسب: Taylor, P, وآخرون
منشور في: (2017)

Use of magnetic resonance imaging to support dose selection in a phase II trial of baricitinib combined with conventional synthetic disease-modifying antirheumatic drugs in rheumatoid arthritis
حسب: Peterfy, C, وآخرون
منشور في: (2019)

Cost-effectiveness analysis of baricitinib versus adalimumab for the treatment of moderate-to-severe rheumatoid arthritis in Spain
حسب: Schlueter M, وآخرون
منشور في: (2019-06-01)

Cardiovascular safety - Update from up to 6 years of treatment with baricitinib in rheumatoid arthritis clinical trials
حسب: Weinblatt, M, وآخرون
منشور في: (2018)

24-WEEK RESULTS OF A BLINDED PHASE IIB DOSE-RANGING STUDY OF BARICITINIB, AN ORAL JAK1/JAK2 INHIBITOR, IN COMBINATION WITH TRADITIONAL DMARDS IN PATIENTS WITH RHEUMATOID ARTHRITIS
حسب: Taylor, P, وآخرون
منشور في: (2013)

Baricitinib for the treatment of rheumatoid arthritis
حسب: Ivan Urits, وآخرون
منشور في: (2020-12-01)

Achieving pain control in rheumatoid arthritis with baricitinib or ddalimumab plus methotrexate: Results from the RA-BEAM Trial
حسب: Taylor, P, وآخرون
منشور في: (2019)

24-Week Results of a Blinded Phase 2b Dose-Ranging Study of Baricitinib, an Oral Janus Kinase 1/Januse Kinase 2 Inhibitor, in Combination with Traditional Disease Modifying Antirheumatic Drugs in Patients with Rheumatoid Arthritis.
حسب: Genovese, M, وآخرون
منشور في: (2012)

Patient disease trajectories in baricitinib-treated patients with rheumatoid arthritis and inadequate response to methotrexate
حسب: Taylor, P, وآخرون
منشور في: (2019)

Lack of clinical disease activity response at 4 weeks of baricitinib treatment as a negative predictor of remission at weeks 12 and 24 in patients with rheumatoid arthritis: results from two phase 3 studies (RA-BEAM and RA-BEGIN)
حسب: Tanaka, Y, وآخرون
منشور في: (2021)

Magnetic Resonance Imaging Substudy in a Phase 2b Dose-Ranging Study of Baricitinib, an Oral Janus Kinase 1/Janus Kinase 2 Inhibitor, in Combination with Traditional Disease-Modifying Antirheumatic Drugs in Patients with Rheumatoid Arthritis.
حسب: Peterfy, C, وآخرون
منشور في: (2012)

Low rates of radiographic progression of structural joint damage over 2 years of baricitinib treatment in patients with rheumatoid arthritis
حسب: Désirée van der Heijde, وآخرون
منشور في: (2019-06-01)

Comparative effectiveness in pain and haq-di improvement for baricitinib versus adalimumab, tocilizumab, and tofacitinib monotherapies in csdmard-naÏve rheumatoid arthritis patients: a matching-adjusted indirect comparison (MAIC)
حسب: Fautrel, B, وآخرون
منشور في: (2018)

Cost per number needed to treat and treatment cost of baricitinib versus adalimumab on rheumatoid arthritis treatment in the brazilian private healthcare system
حسب: Bruno Corona Prandi, وآخرون
منشور في: (2023-02-01)

Impact of high rheumatoid factor levels on treatment outcomes with certolizumab pegol and adalimumab in patients with rheumatoid arthritis
حسب: Smolen, JS, وآخرون
منشور في: (2024)

Baricitinib exposure during pregnancy in rheumatoid arthritis
حسب: Giulia Costanzo, وآخرون
منشور في: (2020-01-01)

Baricitinib: Early vs. delayed start in patients with rheumatoid arthritis
حسب: Taylor, P, وآخرون
منشور في: (2018)

A JAK inhibitor for treatment of rheumatoid arthritis: the baricitinib experience
حسب: Taylor, PC, وآخرون
منشور في: (2023)

Patient disease trajectories in rheumatoid arthritis patients treated with baricitinib 4-mg in 4 phase 3 clinical studies
حسب: Taylor, PC, وآخرون
منشور في: (2023)

Patient Disease Trajectories in Rheumatoid Arthritis Patients Treated with Baricitinib 4-mg in Four Phase 3 Clinical Studies
حسب: Peter C. Taylor, وآخرون
منشور في: (2023-01-01)

Cutaneous eruption after commencing baricitinib for rheumatoid arthritis
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منشور في: (2024-06-01)