Physiological roles of NAADP-mediated Ca2+ signaling.

Physiological roles of NAADP-mediated Ca2+ signaling.

Nicotinic acid dinucleotide phosphate (NAADP) is unique amongst Ca(2+) mobilizing messengers in that its principal function is to mobilize Ca(2+) from acidic organelles. Early studies indicated that it was likely that NAADP activates a novel Ca(2+) release channel distinct from the well characterize...

Bibliografski detalji
Glavni autori:	Galione, A, Parrington, J, Funnell, T
Format:	Journal article
Jezik:	English
Izdano:	2011

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NAADP receptors.
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Hippocampal mGluR1-dependent long-term potentiation requires NAADP-mediated acidic store Ca2+ signaling
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Unique kinetics of nicotinic acid-adenine dinucleotide phosphate (NAADP) binding enhance the sensitivity of NAADP receptors for their ligand.
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