Comparison of neutral proteases and collagenase class I as essential enzymes for human islet isolation

Background. Efficient islet isolation requires synergistic interaction between collagenase class I (CI) and class II (CII). The CI degradation alters the ratio between CI and CII and is responsible for batch-to-batch variations. This study compares the role of neutral protease (NP) plus clostripain...

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Hlavní autoři: Brandhorst, H, Kurfürst, M, Johnson, P, Korsgren, O, Brandhorst, D
Médium: Journal article
Jazyk:English
Vydáno: Lippincott, Williams and Wilkins 2015