Reversal of charge selectivity in transmembrane protein pores by using noncovalent molecular adapters.

Reversal of charge selectivity in transmembrane protein pores by using noncovalent molecular adapters.

In this study, the charge selectivity of staphylococcal alpha-hemolysin (alphaHL), a bacterial pore-forming toxin, is manipulated by using cyclodextrins as noncovalent molecular adapters. Anion-selective versions of alphaHL, including the wild-type pore and various mutants, become more anion selecti...

書目詳細資料
Main Authors:	Gu, L, Dalla Serra, M, Vincent, J, Vigh, G, Cheley, S, Braha, O, Bayley, H
格式:	Journal article
語言:	English
出版:	2000

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