Reversal of charge selectivity in transmembrane protein pores by using noncovalent molecular adapters.

Reversal of charge selectivity in transmembrane protein pores by using noncovalent molecular adapters.

In this study, the charge selectivity of staphylococcal alpha-hemolysin (alphaHL), a bacterial pore-forming toxin, is manipulated by using cyclodextrins as noncovalent molecular adapters. Anion-selective versions of alphaHL, including the wild-type pore and various mutants, become more anion selecti...

Полное описание

Библиографические подробности
Главные авторы:	Gu, L, Dalla Serra, M, Vincent, J, Vigh, G, Cheley, S, Braha, O, Bayley, H
Формат:	Journal article
Язык:	English
Опубликовано:	2000

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