Dexamethasone, cerebrospinal fluid matrix metalloproteinase concentrations and clinical outcomes in tuberculous meningitis.

BACKGROUND: Adjunctive dexamethasone reduces mortality from tuberculous meningitis, but how it produces this effect is not known. Matrix metalloproteinases (MMPs) are important in the immunopathology of many inflammatory CNS diseases thus we hypothesized that that their secretion is important in TBM...

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Hlavní autoři: Green, J, Tran, C, Farrar, J, Nguyen, M, Nguyen, P, Dinh, S, Ho, N, Ly, C, Tran, H, Friedland, J, Thwaites, G
Médium: Journal article
Jazyk:English
Vydáno: Public Library of Science 2009