Flucytosine and cryptococcosis: time to urgently address the worldwide accessibility of a 50-year-old antifungal.

Current, widely accepted guidelines for the management of HIV-associated cryptococcal meningoencephalitis (CM) recommend amphotericin B combined with flucytosine (5-FC) for ≥2 weeks as the initial induction treatment of choice. However, access to flucytosine in Africa and Asia, where disease burden...

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Detalhes bibliográficos
Principais autores: Loyse, A, Dromer, F, Day, J, Lortholary, O, Harrison, T
Formato: Journal article
Idioma:English
Publicado em: 2013