Use of a large Stokes-shift fluorophore to increase the multiplexing capacity of a point-of-care DNA diagnostic device.
The intense demand for fluorescence-based point of care (POC) DNA diagnostics is driving developments to reduce the size of instrumentation, imposing limitations on the optical hardware that can be included. Here we describe a combination of instrumentation and fluorogenic probes to detect three flu...
Main Authors: | , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2013
|
_version_ | 1826280358853738496 |
---|---|
author | Richardson, J Morgan, T Andreou, M Brown, T |
author_facet | Richardson, J Morgan, T Andreou, M Brown, T |
author_sort | Richardson, J |
collection | OXFORD |
description | The intense demand for fluorescence-based point of care (POC) DNA diagnostics is driving developments to reduce the size of instrumentation, imposing limitations on the optical hardware that can be included. Here we describe a combination of instrumentation and fluorogenic probes to detect three fluorophores using two excitation and two detection channels. |
first_indexed | 2024-03-07T00:12:31Z |
format | Journal article |
id | oxford-uuid:79baca1e-7022-4079-94f5-5c66e39037e4 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T00:12:31Z |
publishDate | 2013 |
record_format | dspace |
spelling | oxford-uuid:79baca1e-7022-4079-94f5-5c66e39037e42022-03-26T20:39:11ZUse of a large Stokes-shift fluorophore to increase the multiplexing capacity of a point-of-care DNA diagnostic device.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:79baca1e-7022-4079-94f5-5c66e39037e4EnglishSymplectic Elements at Oxford2013Richardson, JMorgan, TAndreou, MBrown, TThe intense demand for fluorescence-based point of care (POC) DNA diagnostics is driving developments to reduce the size of instrumentation, imposing limitations on the optical hardware that can be included. Here we describe a combination of instrumentation and fluorogenic probes to detect three fluorophores using two excitation and two detection channels. |
spellingShingle | Richardson, J Morgan, T Andreou, M Brown, T Use of a large Stokes-shift fluorophore to increase the multiplexing capacity of a point-of-care DNA diagnostic device. |
title | Use of a large Stokes-shift fluorophore to increase the multiplexing capacity of a point-of-care DNA diagnostic device. |
title_full | Use of a large Stokes-shift fluorophore to increase the multiplexing capacity of a point-of-care DNA diagnostic device. |
title_fullStr | Use of a large Stokes-shift fluorophore to increase the multiplexing capacity of a point-of-care DNA diagnostic device. |
title_full_unstemmed | Use of a large Stokes-shift fluorophore to increase the multiplexing capacity of a point-of-care DNA diagnostic device. |
title_short | Use of a large Stokes-shift fluorophore to increase the multiplexing capacity of a point-of-care DNA diagnostic device. |
title_sort | use of a large stokes shift fluorophore to increase the multiplexing capacity of a point of care dna diagnostic device |
work_keys_str_mv | AT richardsonj useofalargestokesshiftfluorophoretoincreasethemultiplexingcapacityofapointofcarednadiagnosticdevice AT morgant useofalargestokesshiftfluorophoretoincreasethemultiplexingcapacityofapointofcarednadiagnosticdevice AT andreoum useofalargestokesshiftfluorophoretoincreasethemultiplexingcapacityofapointofcarednadiagnosticdevice AT brownt useofalargestokesshiftfluorophoretoincreasethemultiplexingcapacityofapointofcarednadiagnosticdevice |