Is there a higher genetic load of susceptibility loci in familial ankylosing spondylitis?

Is there a higher genetic load of susceptibility loci in familial ankylosing spondylitis?

Show other versions (1)

Several genetic risk variants for ankylosing spondylitis (AS) have been identified in genome-wide association studies. Our objective was to examine whether familial AS cases have a higher genetic load of these susceptibility variants.Overall, 502 AS patients were examined, consisting of 312 patients...

Full description

Bibliographic Details
Main Authors:	Joshi, R, Reveille, J, Brown, M, Weisman, M, Ward, M, Gensler, L, Wordsworth, B, Evans, D, Assassi, S
Format:	Journal article
Language:	English
Published:	2012

Similar Items

Is There a Higher Genetic Load of Susceptibility Loci in Familial Ankylosing Spondylitis?
by: Joshi, R, et al.
Published: (2011)

Genetics of ankylosing spondylitis.
by: Brown, M, et al.
Published: (2002)

Susceptibility to ankylosing spondylitis.
by: Carter, N, et al.
Published: (2000)

Genetic susceptibility to ankylosing spondylitis.
by: Sims, A, et al.
Published: (2004)

A genome-wide screen for susceptibility loci in ankylosing spondylitis.
by: Brown, M, et al.
Published: (1998)

Diagnostic capacity of genetic tests in Ankylosing spondylitis can exceed MRI scanning
by: Evans, D, et al.
Published: (2008)

The X-chromosome and susceptibility to ankylosing spondylitis.
by: Hoyle, E, et al.
Published: (2000)

Interleukin-1 and susceptibility to ankylosing spondylitis
by: Edwards, S, et al.
Published: (2001)

Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci.
by: Laval, S, et al.
Published: (2001)

Axial spondyloarthritis: A new disease entity, not necessarily early ankylosing spondylitis
by: Robinson, P, et al.
Published: (2012)

Axial spondyloarthritis: A new disease entity, not necessarily early ankylosing spondylitis
by: Robinson, P, et al.
Published: (2013)

Axial spondyloarthritis: a new disease entity, not necessarily early ankylosing spondylitis.
by: Robinson, P, et al.
Published: (2013)

Genomewide association study in Ankylosing spondylitis identifies major Non-MHC genetic determinants of disease susceptibility
by: Reveille, J, et al.
Published: (2008)

Genomewide association study in ankylosing spondylitis identifies major non-MHC genetic determinants of disease susceptibility
by: Reveille, J, et al.
Published: (2008)

Genetic aspects of susceptibility, severity, and clinical expression in ankylosing spondylitis.
by: Brown, M, et al.
Published: (2002)

Identification of major loci controlling clinical manifestations of ankylosing spondylitis.
by: Brown, M, et al.
Published: (2003)

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.
by: Reveille, J, et al.
Published: (2010)

Further investigation of three non-MHC loci associated with ankylosing spondylitis
by: Karaderi, T, et al.
Published: (2008)

Interleukin 23 receptor and susceptibility to ankylosing spondylitis
by: Pointon, J, et al.
Published: (2008)

Il-23r is a major determinant of ankylosing spondylitis risk - The tasc study
by: Reveille, J, et al.
Published: (2007)

Repeated Spinal Mobility Measures and Their Association With Radiographic Damage in Ankylosing Spondylitis
by: Mark C. Hwang, et al.
Published: (2021-06-01)

Secretor status and ankylosing spondylitis.
by: Pal, A, et al.
Published: (1998)

THE ROLE OF ANKH IN ANKYLOSING SPONDYLITIS
by: Timms, A, et al.
Published: (2003)

The role of germline polymorphisms in the T-cell receptor in susceptibility to ankylosing spondylitis.
by: Brown, M, et al.
Published: (1998)

The effect of HLA-DR genes on susceptibility to and severity of ankylosing spondylitis.
by: Brown, M, et al.
Published: (1998)

Confirmation of non-MHC genetic loci by whole genome linkage studies in ankylosing spondylitis.
by: Brown, M, et al.
Published: (2000)

Susceptibility to ankylosing spondylitis in twins: the role of genes, HLA, and the environment.
by: Brown, M, et al.
Published: (1997)

Association study of genes related to bone formation and resorption and the extent of radiographic change in ankylosing spondylitis
by: Cortes, A, et al.
Published: (2015)

TNFR1 and ANKYLOSING SPONDYLITIS
by: Karaderi, T, et al.
Published: (2010)

Polymorphisms of the CYP2D6 gene increase susceptibility to ankylosing spondylitis.
by: Brown, M, et al.
Published: (1998)

Evidence for replication of genetic loci from a whole genome association study of ankylosing spondylitis
by: Pointon, J, et al.
Published: (2008)

Investigation of the role of ANKH in ankylosing spondylitis.
by: Timms, A, et al.
Published: (2003)

Clinical features of ankylosing spondylitis in the UK
by: Farrar, C, et al.
Published: (2008)

ANTXR2 IS ASSOCIATED WITH ANKYLOSING SPONDYLITIS
by: Karaderi, T, et al.
Published: (2014)

CANDIDATE GENES FOR ANKYLOSING SPONDYLITIS
by: Pointon, J, et al.
Published: (2009)

CD14 variants in UK and Finnish ankylosing spondylitis families
by: Pointon, J, et al.
Published: (2006)

Quantitative proteomic screening uncovers candidate diagnostic and monitoring serum biomarkers of ankylosing spondylitis
by: Mark Hwang, et al.
Published: (2023-04-01)

The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene tumour necrosis factor receptor type 1-associated death domain (TRADD).
by: Pointon, J, et al.
Published: (2010)

ARTS1 and ankylosing spondylitis
by: Harvey, D, et al.
Published: (2008)

Harmonization, data management, and statistical issues related to prospective multicenter studies in Ankylosing spondylitis (AS): Experience from the Prospective Study Of Ankylosing Spondylitis (PSOAS) cohort
by: Mohammad H. Rahbar, et al.
Published: (2018-09-01)