A 2,3-butanedione protected chiral glycine equivalent - A new building block for the stereoselective synthesis of enantiopure N-protected α-amino acids
A new chiral glycine equivalent 7 has been synthesised from glycidol using a chiral memory protocol, and its use in the synthesis of N-Z protected α-amino acids was demonstrated in a series of diasteroselective lithium enolate alkylation reactions and subsequent acid hydrolyses.
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2003
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