Functional analysis of mutations in isocitrate dehydrogenase involved in gliomagenesis

<p>The main subject of my thesis is the investigation of mechanisms of glioma tumorigenesis associated with the recently identified mutations in isocitrate dehydrogenase. Gliomas account for 80% of primary brain cancers. They represent a diverse group of tumours, and are graded from I-IV based...

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Bibliographic Details
Main Author: Krell, D
Other Authors: Tomlinson, I
Format: Thesis
Language:English
Published: 2014