The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty.
Concerns now exist about the long-term biological effects of exposure to orthopaedic metal alloys, particularly serum cobalt and chromium ions derived from metal-on-metal wear debris in these patients. A pseudotumour mass complicating metal-on-metal resurfacing arthroplasty has been recognized by or...
Autores principales: | , , , , , , |
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Formato: | Journal article |
Lenguaje: | English |
Publicado: |
2008
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_version_ | 1826280406542974976 |
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author | Harvie, P Giele, H Fang, C Ansorge, O Ostlere, S Gibbons, M Whitwell, D |
author_facet | Harvie, P Giele, H Fang, C Ansorge, O Ostlere, S Gibbons, M Whitwell, D |
author_sort | Harvie, P |
collection | OXFORD |
description | Concerns now exist about the long-term biological effects of exposure to orthopaedic metal alloys, particularly serum cobalt and chromium ions derived from metal-on-metal wear debris in these patients. A pseudotumour mass complicating metal-on-metal resurfacing arthroplasty has been recognized by orthopaedic oncologists and specialist hip units. Pseudotumours may also present with a major nerve palsy. Two cases of femoral neuropathy due to pseudotumour masses caused by metal-on-metal resurfacing arthroplasty are presented. Preoperative neurophysiological studies showed severe and irreversible pathological changes to nerve function with neurohistopathological evidence of complete nerve destruction with a previously unreported pathological appearance. This may represent a previously unrecognized pathological process, possibly 'toxic' in nature, resulting from metal-on-metal wear debris. Prolonged follow-up and detailed clinical assessment of patients after hip resurfacing arthroplasty is advocated with planned and expeditious revision of any patient in whom evidence of femoral neuropathy develops. |
first_indexed | 2024-03-07T00:13:14Z |
format | Journal article |
id | oxford-uuid:79f7bf8c-4251-441f-9adf-10cea39cf5cd |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T00:13:14Z |
publishDate | 2008 |
record_format | dspace |
spelling | oxford-uuid:79f7bf8c-4251-441f-9adf-10cea39cf5cd2022-03-26T20:40:44ZThe treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:79f7bf8c-4251-441f-9adf-10cea39cf5cdEnglishSymplectic Elements at Oxford2008Harvie, PGiele, HFang, CAnsorge, OOstlere, SGibbons, MWhitwell, DConcerns now exist about the long-term biological effects of exposure to orthopaedic metal alloys, particularly serum cobalt and chromium ions derived from metal-on-metal wear debris in these patients. A pseudotumour mass complicating metal-on-metal resurfacing arthroplasty has been recognized by orthopaedic oncologists and specialist hip units. Pseudotumours may also present with a major nerve palsy. Two cases of femoral neuropathy due to pseudotumour masses caused by metal-on-metal resurfacing arthroplasty are presented. Preoperative neurophysiological studies showed severe and irreversible pathological changes to nerve function with neurohistopathological evidence of complete nerve destruction with a previously unreported pathological appearance. This may represent a previously unrecognized pathological process, possibly 'toxic' in nature, resulting from metal-on-metal wear debris. Prolonged follow-up and detailed clinical assessment of patients after hip resurfacing arthroplasty is advocated with planned and expeditious revision of any patient in whom evidence of femoral neuropathy develops. |
spellingShingle | Harvie, P Giele, H Fang, C Ansorge, O Ostlere, S Gibbons, M Whitwell, D The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty. |
title | The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty. |
title_full | The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty. |
title_fullStr | The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty. |
title_full_unstemmed | The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty. |
title_short | The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty. |
title_sort | treatment of femoral neuropathy due to pseudotumour caused by metal on metal resurfacing arthroplasty |
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