The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty.

Concerns now exist about the long-term biological effects of exposure to orthopaedic metal alloys, particularly serum cobalt and chromium ions derived from metal-on-metal wear debris in these patients. A pseudotumour mass complicating metal-on-metal resurfacing arthroplasty has been recognized by or...

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Autores principales: Harvie, P, Giele, H, Fang, C, Ansorge, O, Ostlere, S, Gibbons, M, Whitwell, D
Formato: Journal article
Lenguaje:English
Publicado: 2008
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author Harvie, P
Giele, H
Fang, C
Ansorge, O
Ostlere, S
Gibbons, M
Whitwell, D
author_facet Harvie, P
Giele, H
Fang, C
Ansorge, O
Ostlere, S
Gibbons, M
Whitwell, D
author_sort Harvie, P
collection OXFORD
description Concerns now exist about the long-term biological effects of exposure to orthopaedic metal alloys, particularly serum cobalt and chromium ions derived from metal-on-metal wear debris in these patients. A pseudotumour mass complicating metal-on-metal resurfacing arthroplasty has been recognized by orthopaedic oncologists and specialist hip units. Pseudotumours may also present with a major nerve palsy. Two cases of femoral neuropathy due to pseudotumour masses caused by metal-on-metal resurfacing arthroplasty are presented. Preoperative neurophysiological studies showed severe and irreversible pathological changes to nerve function with neurohistopathological evidence of complete nerve destruction with a previously unreported pathological appearance. This may represent a previously unrecognized pathological process, possibly 'toxic' in nature, resulting from metal-on-metal wear debris. Prolonged follow-up and detailed clinical assessment of patients after hip resurfacing arthroplasty is advocated with planned and expeditious revision of any patient in whom evidence of femoral neuropathy develops.
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spelling oxford-uuid:79f7bf8c-4251-441f-9adf-10cea39cf5cd2022-03-26T20:40:44ZThe treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:79f7bf8c-4251-441f-9adf-10cea39cf5cdEnglishSymplectic Elements at Oxford2008Harvie, PGiele, HFang, CAnsorge, OOstlere, SGibbons, MWhitwell, DConcerns now exist about the long-term biological effects of exposure to orthopaedic metal alloys, particularly serum cobalt and chromium ions derived from metal-on-metal wear debris in these patients. A pseudotumour mass complicating metal-on-metal resurfacing arthroplasty has been recognized by orthopaedic oncologists and specialist hip units. Pseudotumours may also present with a major nerve palsy. Two cases of femoral neuropathy due to pseudotumour masses caused by metal-on-metal resurfacing arthroplasty are presented. Preoperative neurophysiological studies showed severe and irreversible pathological changes to nerve function with neurohistopathological evidence of complete nerve destruction with a previously unreported pathological appearance. This may represent a previously unrecognized pathological process, possibly 'toxic' in nature, resulting from metal-on-metal wear debris. Prolonged follow-up and detailed clinical assessment of patients after hip resurfacing arthroplasty is advocated with planned and expeditious revision of any patient in whom evidence of femoral neuropathy develops.
spellingShingle Harvie, P
Giele, H
Fang, C
Ansorge, O
Ostlere, S
Gibbons, M
Whitwell, D
The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty.
title The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty.
title_full The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty.
title_fullStr The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty.
title_full_unstemmed The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty.
title_short The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty.
title_sort treatment of femoral neuropathy due to pseudotumour caused by metal on metal resurfacing arthroplasty
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