A multicentre randomised controlled trial of Transfusion Indication Threshold Reduction on transfusion rates, morbidity and health-care resource use following cardiac surgery (TITRe2).

The study found that a restrictive transfusion threshold of red blood cells is not superior to a liberal threshold after cardiac surgery. This finding supports restrictive transfusion due to reduced consumption and costs of red blood cells. However, secondary findings create uncertainty about recomm...

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Main Authors: Reeves, B, Pike, K, Rogers, C, Brierley, R, Stokes, E, Wordsworth, S, Nash, R, Miles, A, Mumford, A, Cohen, A, Angelini, G, Murphy, G
Format: Journal article
Language:English
Published: NIHR Health Technology Assessment Programme 2016
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author Reeves, B
Pike, K
Rogers, C
Brierley, R
Stokes, E
Wordsworth, S
Nash, R
Miles, A
Mumford, A
Cohen, A
Angelini, G
Murphy, G
author_facet Reeves, B
Pike, K
Rogers, C
Brierley, R
Stokes, E
Wordsworth, S
Nash, R
Miles, A
Mumford, A
Cohen, A
Angelini, G
Murphy, G
author_sort Reeves, B
collection OXFORD
description The study found that a restrictive transfusion threshold of red blood cells is not superior to a liberal threshold after cardiac surgery. This finding supports restrictive transfusion due to reduced consumption and costs of red blood cells. However, secondary findings create uncertainty about recommending restrictive transfusion and prompt a new hypothesis that liberal transfusion may be superior after cardiac surgery.
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spelling oxford-uuid:7a0312af-17fa-4c10-96bb-00b82e6aeeae2022-03-26T20:41:02ZA multicentre randomised controlled trial of Transfusion Indication Threshold Reduction on transfusion rates, morbidity and health-care resource use following cardiac surgery (TITRe2).Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7a0312af-17fa-4c10-96bb-00b82e6aeeaeEnglishSymplectic Elements at OxfordNIHR Health Technology Assessment Programme2016Reeves, BPike, KRogers, CBrierley, RStokes, EWordsworth, SNash, RMiles, AMumford, ACohen, AAngelini, GMurphy, GThe study found that a restrictive transfusion threshold of red blood cells is not superior to a liberal threshold after cardiac surgery. This finding supports restrictive transfusion due to reduced consumption and costs of red blood cells. However, secondary findings create uncertainty about recommending restrictive transfusion and prompt a new hypothesis that liberal transfusion may be superior after cardiac surgery.
spellingShingle Reeves, B
Pike, K
Rogers, C
Brierley, R
Stokes, E
Wordsworth, S
Nash, R
Miles, A
Mumford, A
Cohen, A
Angelini, G
Murphy, G
A multicentre randomised controlled trial of Transfusion Indication Threshold Reduction on transfusion rates, morbidity and health-care resource use following cardiac surgery (TITRe2).
title A multicentre randomised controlled trial of Transfusion Indication Threshold Reduction on transfusion rates, morbidity and health-care resource use following cardiac surgery (TITRe2).
title_full A multicentre randomised controlled trial of Transfusion Indication Threshold Reduction on transfusion rates, morbidity and health-care resource use following cardiac surgery (TITRe2).
title_fullStr A multicentre randomised controlled trial of Transfusion Indication Threshold Reduction on transfusion rates, morbidity and health-care resource use following cardiac surgery (TITRe2).
title_full_unstemmed A multicentre randomised controlled trial of Transfusion Indication Threshold Reduction on transfusion rates, morbidity and health-care resource use following cardiac surgery (TITRe2).
title_short A multicentre randomised controlled trial of Transfusion Indication Threshold Reduction on transfusion rates, morbidity and health-care resource use following cardiac surgery (TITRe2).
title_sort multicentre randomised controlled trial of transfusion indication threshold reduction on transfusion rates morbidity and health care resource use following cardiac surgery titre2
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