Functional genomic analysis of a RUNX3 polymorphism associated with ankylosing spondylitis

Functional genomic analysis of a RUNX3 polymorphism associated with ankylosing spondylitis

Objective To investigate the functional consequences of the single-nucleotide polymorphism rs4648889 in a putative enhancer upstream of the RUNX3 promoter associated with susceptibility to ankylosing spondylitis (AS). Methods Using nuclear extracts from Jurkat cells and primary human CD8+ T cells,...

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Bibliographic Details
Main Authors:	Vecellio, M, Chen, L, Cohen, CJ, Cortes, A, Li, Y, Bonham, S, Selmi, C, Brown, MA, Fischer, R, Knight, JC, Wordsworth, BP
Format:	Journal article
Language:	English
Published:	Wiley 2021

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