Flexible strategy for the synthesis of pyrrolizidine alkaloids.
A general strategy for the production of pyrrolizidine alkaloids is described, starting from intermediate (+)-9. The key features are diastereoselective dihydroxylation, inversion at the ring junction by hydroboration of an enamine, and ring closure to form the bicyclo ring system. This route is att...
المؤلفون الرئيسيون: | , , , , , |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2008
|