Flexible strategy for the synthesis of pyrrolizidine alkaloids.

A general strategy for the production of pyrrolizidine alkaloids is described, starting from intermediate (+)-9. The key features are diastereoselective dihydroxylation, inversion at the ring junction by hydroboration of an enamine, and ring closure to form the bicyclo ring system. This route is att...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Donohoe, T, Thomas, R, Cheeseman, MD, Rigby, C, Bhalay, G, Linney, I
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2008