Haemophilus influenzae type b vaccine failure in children is associated with inadequate production of high-quality antibody.
BACKGROUND: Despite the excellent immunogenicity of Haemophilus influenzae type b (Hib) conjugate vaccines, breakthrough cases of Hib disease still affect a small proportion of vaccinated children in the United Kingdom. We performed a retrospective study to compare the avidity of antibody directed...
Hauptverfasser: | Lee, Y, Kelly, D, Yu, L, Slack, M, Booy, R, Heath, P, Siegrist, C, Moxon, R, Pollard, A |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2008
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