Haemophilus influenzae type b vaccine failure in children is associated with inadequate production of high-quality antibody.

BACKGROUND: Despite the excellent immunogenicity of Haemophilus influenzae type b (Hib) conjugate vaccines, breakthrough cases of Hib disease still affect a small proportion of vaccinated children in the United Kingdom. We performed a retrospective study to compare the avidity of antibody directed...

Descrición completa

Detalles Bibliográficos
Main Authors: Lee, Y, Kelly, D, Yu, L, Slack, M, Booy, R, Heath, P, Siegrist, C, Moxon, R, Pollard, A
Formato: Journal article
Idioma:English
Publicado: 2008