A short-term increase in cancer risk associated with daytime napping is likely to reflect pre-clinical disease: prospective cohort study.
BACKGROUND: Sleep disturbance, a correlate of which is daytime napping, has been hypothesised to be associated with risk of breast and other cancers. METHODS: We estimated relative risks (RR) of breast and other invasive cancers by the reported frequency of daytime napping in a large prospective coh...
| Main Authors: | , , , , , |
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| 格式: | Journal article |
| 語言: | English |
| 出版: |
2012
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| _version_ | 1826280461820755968 |
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| author | Cairns, B Travis, R Wang, X Reeves, G Green, J Beral, V |
| author_facet | Cairns, B Travis, R Wang, X Reeves, G Green, J Beral, V |
| author_sort | Cairns, B |
| collection | OXFORD |
| description | BACKGROUND: Sleep disturbance, a correlate of which is daytime napping, has been hypothesised to be associated with risk of breast and other cancers. METHODS: We estimated relative risks (RR) of breast and other invasive cancers by the reported frequency of daytime napping in a large prospective cohort of middle-aged women in the UK. RESULTS: During an average of 7.4 years of follow-up, 20 058 breast cancers and 31 856 other cancers were diagnosed. Over the first 4 years of follow-up, daytime napping (sometimes/usually vs rarely/never) was associated with slightly increased risks of breast cancer (RR=1.10, 95% CI 1.06-1.15) and of other cancers (RR=1.12, 1.08-1.15), but the RRs decreased significantly with increasing follow-up time (P=0.001 and P=0.01, respectively, for trend). Four or more years after baseline, there was no elevated risk of breast cancer (RR=1.00, 0.96-1.05), and only marginally greater risk of other cancers (RR=1.04, 1.01-1.07). CONCLUSION: The effect of pre-clinical disease is a likely explanation for the short-term increased risk of breast and other cancers associated with daytime napping. |
| first_indexed | 2024-03-07T00:14:04Z |
| format | Journal article |
| id | oxford-uuid:7a38fb53-bc7d-444e-b49f-40a05bf53c34 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:14:04Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | oxford-uuid:7a38fb53-bc7d-444e-b49f-40a05bf53c342022-03-26T20:42:38ZA short-term increase in cancer risk associated with daytime napping is likely to reflect pre-clinical disease: prospective cohort study.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7a38fb53-bc7d-444e-b49f-40a05bf53c34EnglishSymplectic Elements at Oxford2012Cairns, BTravis, RWang, XReeves, GGreen, JBeral, VBACKGROUND: Sleep disturbance, a correlate of which is daytime napping, has been hypothesised to be associated with risk of breast and other cancers. METHODS: We estimated relative risks (RR) of breast and other invasive cancers by the reported frequency of daytime napping in a large prospective cohort of middle-aged women in the UK. RESULTS: During an average of 7.4 years of follow-up, 20 058 breast cancers and 31 856 other cancers were diagnosed. Over the first 4 years of follow-up, daytime napping (sometimes/usually vs rarely/never) was associated with slightly increased risks of breast cancer (RR=1.10, 95% CI 1.06-1.15) and of other cancers (RR=1.12, 1.08-1.15), but the RRs decreased significantly with increasing follow-up time (P=0.001 and P=0.01, respectively, for trend). Four or more years after baseline, there was no elevated risk of breast cancer (RR=1.00, 0.96-1.05), and only marginally greater risk of other cancers (RR=1.04, 1.01-1.07). CONCLUSION: The effect of pre-clinical disease is a likely explanation for the short-term increased risk of breast and other cancers associated with daytime napping. |
| spellingShingle | Cairns, B Travis, R Wang, X Reeves, G Green, J Beral, V A short-term increase in cancer risk associated with daytime napping is likely to reflect pre-clinical disease: prospective cohort study. |
| title | A short-term increase in cancer risk associated with daytime napping is likely to reflect pre-clinical disease: prospective cohort study. |
| title_full | A short-term increase in cancer risk associated with daytime napping is likely to reflect pre-clinical disease: prospective cohort study. |
| title_fullStr | A short-term increase in cancer risk associated with daytime napping is likely to reflect pre-clinical disease: prospective cohort study. |
| title_full_unstemmed | A short-term increase in cancer risk associated with daytime napping is likely to reflect pre-clinical disease: prospective cohort study. |
| title_short | A short-term increase in cancer risk associated with daytime napping is likely to reflect pre-clinical disease: prospective cohort study. |
| title_sort | short term increase in cancer risk associated with daytime napping is likely to reflect pre clinical disease prospective cohort study |
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