Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation

A major therapeutic challenge is how to replace bone once it is lost. Bone loss is a characteristic of chronic inflammatory and degenerative diseases such as rheumatoid arthritis and osteoporosis. Cells and cytokines of the immune system are known to regulate bone turnover by controlling the differe...

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Bibliographic Details
Main Authors: Nicolaidou, V, Wong, M, Redpath, A, Ersek, A, Baban, D, Williams, L, Cope, A, Horwood, N
Format: Journal article
Language:English
Published: Public Library of Science 2012