Structural and functional characterization of the kindlin-1 pleckstrin homology domain.

Structural and functional characterization of the kindlin-1 pleckstrin homology domain.

Inside-out activation of integrins is mediated via the binding of talin and kindlin to integrin β-subunit cytoplasmic tails. The kindlin FERM domain is interrupted by a pleckstrin homology (PH) domain within its F2 subdomain. Here, we present data confirming the importance of the kindlin-1 PH domain...

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Bibliographic Details
Main Authors:	Yates, L, Lumb, C, Brahme, N, Zalyte, R, Bird, L, De Colibus, L, Owens, R, Calderwood, D, Sansom, MS, Gilbert, R
Format:	Journal article
Language:	English
Published:	2012

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