BRD3 and BRD4 BET bromodomain proteins differentially regulate skeletal myogenesis
Myogenic differentiation proceeds through a highly coordinated cascade of gene activation that necessitates epigenomic changes in chromatin structure. Using a screen of small molecule epigenetic probes we identified three compounds which inhibited myogenic differentiation in C2C12 myoblasts; (+)-JQ1...
Үндсэн зохиолчид: | , , , , , , , |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
Springer Nature
2017
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