Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo

Evidence for distinct human cancer stem cells (CSCs) remains contentious and the degree to which differentcancer cells contribute to propagating malignancies in patients remains unexplored. In low- to intermediate-risk myelodysplastic syndromes (MDS), we establish the existence of rare multipotent M...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Woll, P, Kjällquist, U, Chowdhury, O, Doolittle, H, Wedge, D, Thongjuea, S, Erlandsson, R, Ngara, M, Anderson, K, Deng, Q, Mead, A, Stenson, L, Giustacchini, A, Duarte, S, Giannoulatou, E, Taylor, S, Karimi, M, Scharenberg, C, Mortera-Blanco, T, Macaulay, I, Clark, S, Dybedal, I, Josefsen, D, Fenaux, P, Hokland, P
Format: Journal article
Sprache:English
Veröffentlicht: Cell Press 2014