GroEL accelerates the refolding of hen lysozyme without changing its folding mechanism.

GroEL accelerates the refolding of hen lysozyme without changing its folding mechanism.

The chaperonin GroEL binds folding intermediates of four-disulfidehen lysozyme transiently within its central cavity. Using stopped flow fluorescence we show that GroEL binds early intermediates in folding and accelerates the slow kinetic phase that reflects the reversal of non-native interactions i...

書誌詳細
主要な著者:	Coyle, J, Texter, F, Ashcroft, A, Masselos, D, Robinson, C, Radford, SE
フォーマット:	Journal article
言語:	English
出版事項:	1999

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